Bishop Misenus of Cumae was a legate of Pope Felix II (III) to Constantinople in 483 when the Chalcedonian bishop John Talaia had been exiled from Alexandria and replaced by a Miaphysite, Peter Mongos. John Talaia went then to Rome. The pope addressed a letter (carried by Misenus) to the Emperor Zeno in which he reprimanded him for allowing the deposition of John Talaia, and to Acacius in which he demanded the condemnation of the Miaphysitism, and confirmation of his adherence to the Chalcedonian faith. Later Misenus received additional instructions from Rome in which Felix II (III) convoked Bishop Acacius of Constantinople to come to the synod in Rome to respond to the accusations of John Talaia. Upon his arrival to Abydos in Hellespont he and Bishop Vitalis of Truentum were imprisoned and the papal letters they were carrying were confiscated. Additionally they were threatened to be put to death if they refuse to enter communion with Acacius and Peter Mongus. Misenus agreed to this condition, arrived to Constantinople and together with Vitalis took part in the liturgy celebrated by Acacius during which the name of Peter Mongus was recited from the dyptychs. After their return to Italy, they were excommunicated by the Roman synod for communicating with Acacius and Peter Mongus (considered to be a heretic by Rome) in 484. This excommunication is repeated at the synod in 485. In 495 Misenus composed the petitions to the Pope Gelasius in which he was asking for a pardon and expressing anathemas on Eutyches, Dioscorus, Timoty Aelurus, Peter Mongus. He was received to communion at the council in 495. Gesta de absolutione Miseni is a record of the proceedings of this council. See PCBE, Italie, 2, Caelius Misenus. Kosinski 2002. For a discussion on the schism in Alexandria and the Acacian Schism see also . For a detailed discussion of letter 30 in the context of Gelasian pontificate see Demacopoulos 2013: 81-84.